Level of Neurofilaments in Cerebrospinal Fluid Could Confirm ALS Diagnosis, Study Reports

Measuring neurofilaments in brain and spinal fluid appears to be a reliable way of confirming an ALS diagnosis, Belgian and German researchers report. This finding is important because it takes an average of a year from the appearance of the first symptoms before doctors can diagnose the disease. The discovery could shorten this time. The neurons […]

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Gene Therapy to Strengthen Nerve-Muscle Connection Prevents ALS Progression in Mice

MAY 15, 2017  BY MAGDALENA KEGEL A gene therapy aimed at strengthening the connection between motor neurons and muscle prevented nerve degeneration and increased the life span of mice with amyotrophic lateral sclerosis (ALS), a study showed. Since researchers believe that neurodegeneration in ALS starts at the junction between nerves and muscle, the findings suggest that […]

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Researchers Identify New Gene Mutation Likely Involved in ALS Development

ALS News Today, May 18, 2017, written by Joana Fernandes, PHD. Mutations in the UBQLN4 gene may contribute to the development of amyotrophic lateral sclerosis (ALS), according to recent research. The study, “A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis,” was published in the journal eLife. Over the years, researchers have identified numerous genes linked to […]

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